Imaging Transport Across the Maternal-Fetal Barrier

Folate_IVIS_ImageWhen combined with contrast agents, photoacoustic imaging can be used to investigate the transport of key molecules across the placental barrier. For example, placental transport of folate, a critical nutrient for development, may be altered in the presence of specific medications. How the presence of specific medications changes the folate available to the fetus is being studied with our imaging techniques. This work is funded by a Research Competitiveness Subprogram grant from the Louisiana Board of Regents. 

References

Huda, K, Wu, C, Sider, J, Ermilov, S. Bayer, CL “Photoacoustic Tomography for Longitudinal Monitoring of Targeted Contrast Agents”, Optical Society of America Biophotonics Congress: Optics in the Life Sciences, April 19, 2019, Tucson, AZ.

Escott, ME, Lawrence, DJ, Cook, J, Bayer, CL “Oxygen Loaded Nanodroplets as a Theranostic for High Risk Pregnancies Using Multimodal Ultrasound and Photoacoustic Imaging”. Optical Society of America Biophotonics Congress: Optics in the Life Sciences, April 18, 2019, Tucson, AZ.

Sider, J, Wu, C, Hirsch, R, Ermilov, S, Bayer, CL. “Multimodal tomographic fluorescent and photoacoustic imaging of placental function”, Biomedical Engineering Society Annual Meeting, Atlanta, GA, October 18, 2018.

Wu, C, Bayer, CL, “Photoacoustic imaging to measure reduced placental transport of folate”, World Molecular Imaging Congress, Seattle, WA, September 12, 2018

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